Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders
B12 injections start to work fast, usually making a difference in how you feel within 48 to 72 hours
Medically reviewed by Dr Clair Grainger Last reviewed: 29 Jun 2026 With Superdrug Online Doctor you can message our Doctors for FREE via your patient account
Routine labs may look normal even when local gut, skin, or connective-tissue symptoms remain
These patients who do not fit the criteria but who remain undiagnosed B12 deficient patients become very expensive for the NHS to look after
When administered by an experienced and medically trained practitioner the procedure is very safe with complications being extremely rare