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FDA materials flag compounded injectable GHK-Cu as a safety concern because of limited human safety data, aggregation risk, peptide-related impurities, and possible immunogenicity [8]

However, in March 2026 the FDA approved the injectable Wegovy HD, manufactured by Novo Nordisk, that has a 7.2 mg dose three times higher

The peptide accelerates healing through multiple mechanisms

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The 'Long R3' modification extends IGF-1 half-life from 10 minutes to 2030 hours by reducing IGF-binding protein affinity 100-fold, creating sustained anabolic signalling endogenous IGF-1 cannot match

Medical contraindications Personal or family history of medullary thyroid carcinoma