Reduction in White Adipose Tissue Mass : Preclinical data indicate a marked reduction in white adipose tissue following administration of 5-Amino-1MQ
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In dextran sulphate sodium (DSS)-induced colitis mice, the most commonly used preclinical IBD model, injected MOTS-c significantly reduced colon shortening and histological damage, lowered pro-inflammatory cytokines and plasma myeloperoxidase, and curbed macrophage and neutrophil activity
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Pernicious anemia is a chronic condition characterized by the inability to absorb vitamin B12, leading to deficiency and related complications. Other issues like problems after stomach surgery or diseases like Crohns also might need Vitamin B12 injections
What they did: A very harsh model, they ligated the inferior vena cava (vena cava inferior) in rats, which is the main channel for blood returning to the heart