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A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association

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Repeated exposure can trigger antibody formation against the peptide sequence, which theoretically could cross-react with endogenous Klotho protein and suppress the bodys natural protective signaling

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Many Canadians find that taking their supplements with a light snack helps prevent the "supplement nausea" that sometimes occurs when taking concentrated liquids on an empty stomach