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doi:10.1017/S109285292100002X
Interestingly, considering that CCS52B expression is restricted to early phases of the cell cycle (G2/M and M-phase) unlike the A-types (late M-phase to G2-phase) effect of MTX on CCS52B expression goes in accordance with mediation of mitotic cell cycle arrest at S phase
In an experiment from a single representative donor, antagonizing the GLP-1R failed to reduce tirzepatide-stimulated insulin secretion, whereas antagonizing the GIPR reduced insulin secretion by ~55% (Fig