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On September 20, 2019, it was approved as Rybelsus, the first form of a GLP-1 approved as a diabetes treatment
In men, obesity and insulin resistance are associated with low testosterone, poorer sperm parameters and lower chances of conception
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Concerns center around important nutrients that may be lost due to the appetite suppressing effects of GLP-1s, which work by delaying gastric emptying to make patients feel full longer
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It may be a good fit for patients who want a proven GLP-1 pathway, are newer to this medication class, prefer a simpler mechanism, or want a balance between appetite support and tolerability
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