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Chloramphenicol should be discontinued if anemia attributable to chloramphenicol is noted during periodic blood studies, which should be done approximately every 2 days during chloramphenicol receipt

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The rationale is complementary: MOTS-c activates AMPK to push tissue toward burning fuel rather than storing it [2], while 5-Amino-1MQ inhibits NNMT to preserve the NAD+ pool those pathways draw on [4][5]

One case in the broader dataset ran a continuous protocol for nine months

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