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Include Exercise, Especially Strength Training: To protect your muscles and bones during weight loss, make exercise a part of your routine

If you're maintaining a verified caloric deficit (tracked intake, not estimated), results should appear by week 4

Normal: mild redness, slight tenderness or bruising, a small bump, or mild itching usually gone within 13 days

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In TRIUMPH-3, the most common adverse events with retatrutide 9 mg, retatrutide 12 mg, and placebo were diarrhea (30.1%, 24.4%, and 8.7%), nausea (21.7%, 22.4%, and 5.8%), constipation (18.0%, 15.7%, and 7.1%), decreased appetite (13.5%, 14.5%, and 3.0%), and hyperglycemia (3.9%, 3.1%, and 13.4%)

Researchers using intranasal retatrutide should monitor the same parameters as those using the injectable form: body weight, appetite changes, gastrointestinal symptoms, blood pressure, and heart rate