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Link (ScienceDirect) Pizzorno J
Wang A, Aragaki AK, Tang JY, Kurian AW, Manson JE, Chlebowski RT, Simon M, Desai P, Wassertheil-Smoller S, Liu S (2016) Statin use and all-cancer survival: prospective results from the Womens Health Initiative
Studies have identified interactions between the mTOR signaling pathway and GPX4 expression, demonstrating that use of the classical ferroptosis activator, RSL3, can additionally block mTOR activation 9
The pharma has previously announced that REDEFINE 1 is expected to read out by the end of the year, while data from REDEFINE 2 are expected in the first half of 2025
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