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Subcutaneous delivery supports controlled systemic exposure and extended receptor engagement in experimental protocols

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GSH-dependent mitochondrial functions are influenced by changes in levels of cytosolic GSH because GSH is synthesized in the cytosol and must be imported into the mitochondria to exert its function as antioxidant 122,123

The pain intensity ratings were assessed with a VAS for weekly average pain (VASavr) and maximum pain during the last week (VASmax)

Even when stool tests look borderline, these chemical byproducts can still be active

Reported changes tend to be gradual and cumulative rather than immediate