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Following the PRISMA 2020 guidance, five databases were searched from inception to 30 September, 2025

Indeed, local Ex4 infusion into the LDTg suppresses alcohol-induced locomotor stimulation, dopamine release in the NAc, memory of alcohol reward, and alcohol drinking in male rodents (Vallof et al., 2019a)

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Other compounds like mazdutide and survodutide are progressing through development pipelines

These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite

Consider Fermented Foods A healthy gut microbiome is linked to higher natural GLP-1 production