Among 51 ME/CFS patients treated in this fashion, 2/3 reported improvement, accompanied by an increase in number of steps per day, an increase in the physical functioning scale of the RAND-36, and an improvement in the CIS20r fatigue scale
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A potential caveat in this study is that not all women will have poor vitamin B 12 status, and if the proportion of women with adequate status is high, this will reduce our statistical power which may result in failure to detect important differences
[8] Early small-scale research suggested it may stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (fat storage), with preliminary data indicating it may not significantly affect blood glucose or insulin-like growth factor-1 (IGF-1) levels
Therefore, serum potassium levels and platelet count should be monitored carefully during therapy [see Dosage and Administration (2.3)]
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