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An important aspect of drug repositioning is to identify a compound that could also overcome the obstacle of drug resistance in cancer therapy

It is used to treat growth hormone deficiency in both children and adults, and has been found to be safe and effective in clinical trials

(5) In this same study, the 50% increase in these levels did not result in adverse effects (excessive levels of GH) due to a protective feedback mechanism

However, there was also a strong placebo effect, so the authors recommended reproducing the study with a larger group and longer duration

Shiming Z, Mak K-K, Balijepalli MK, Chakravarthi S, Pichika MR

J Diabetes Metab 12:869