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All GLP-1 receptor agonists slow gastric emptying through the same biological mechanism, so both semaglutide and tirzepatide produce similar digestive side effects during the adjustment phase

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Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose

Moreover, RIPK3 expression exhibits spatiotemporal heterogeneity [56]