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De Regil, World Health Organization Guideline on the Use and Indications of Glucagon-Like Peptide-1 Therapies for the Treatment of Obesity in Adults, JAMA , Dec

Wegovy is indicated for lowering body weight in obese and overweight patients with at least one weight-related disease and treating metabolic dysfunction-associated steatohepatitis (MASH) in patients with mild to moderate liver fibrosis

Several factors may contribute to this change

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According to a systematic review by Cochrane, semaglutide produces clinically significant weight loss compared to placebo , with most side effects being mild to moderate in severity

Ozempic is a medication containing semaglutide, a synthetic analog of GLP-1 specifically designed to enhance and extend these beneficial effects