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I think this modification can reshape the future of the medicine, says Lees mentor, Junha Jeon, a chemist at the University of Texas at Arlington

Mean patient age was about 58

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Compounded GLP-1 medications are custom-made by specialty pharmacies using active ingredients like semaglutide and tirzepatide, often at a lower cost but "compounded" doesn't mean "generic." "Compounded medications are not FDA-approved and don't undergo the same premarket review for safety, effectiveness or manufacturing consistency, even though the active ingredients have been extensively studied and used in approved drugs," explains Braverman

The conversation about what to say when requesting GLP-1 options from your provider can make a significant difference in the alternatives presented to you