when tirzepatide doesn't work what if isn't working you're taking a GLP-1 medication like semaglutide or Tirzepatide Not Working? Causes &

Weight reduction was 9.6% with semaglutide versus 3.4% with placebo

GLP-1, or glucagon-like peptide-1, is an incretin hormone produced in the intestine that plays a crucial role in regulating blood sugar levels

By engineering drugs that mimic these hormones (called agonists ) with a longer half-life

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Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor

Once you have reached your ideal body weight, you can discontinue the GLP-1. Its also still unclear if the drugs make it into semen or breast milk, so they shouldnt be used while trying to conceive or breastfeeding