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There are several high-resolution X-ray crystal structures available both of the protein alone and also complexed with a variety of inhibitors [216]

These are research figures, framed for research use only

Moreover, the use of GST 4QN as a tag reduced fused p53 aggregation and enhanced the induction of p21 transcription and apoptosis in cells treated with 5-fluorouracil (5-FU)

The blend cannot be split into its components after reconstitution, so a protocol requiring the two at an independently chosen ratio needs separate vials rather than this format

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These side effects are usually mild and tend to improve over time