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current UK anaesthetic guidance advises holding GLP-1 receptor agonists for 12 weeks before surgery due to delayed gastric emptying and aspiration risk Patients should be counselled that weight loss may be slower or temporarily plateau during corticosteroid treatment, but this does not necessarily mean Wegovy should be discontinued

Food and Drug Administration (FDA) in 2022

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Mood Changes: B12 deficiency can affect mood, leading to symptoms such as irritability, depression, or anxiety