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Achieving nearly 30% weight loss with a medication challenges previous assumptions about the upper limits of drug-induced weight reduction and brings us closer to the efficacy seen with bariatric surgery (30-40% weight loss), but without the surgical risks and recovery time
It has not yet received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)
Similar results were reported with quercetin (181, 182)
The scope of use for the anti-obesity drug Wegovy (active ingredient semaglutide) is expanding beyond weight loss to include the prevention of cardiovascular disease, improvement of fatty liver, mental health benefits, and enhanced fertility
doi: 10.1007/S11882-004-0056-7 30 ZemanK
Starting with very small meals, avoiding trigger foods, and following the gradual dose escalation schedule significantly reduces nausea severity
