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Nature 522, 309314
2017;169(1):132-147.e16
Oral B12 supplementation generally takes longer to produce noticeable effects than intramuscular injections, with patients typically experiencing improvements within 24 weeks
Obesity has a strong biological basis involving hormonal signaling, genetic predisposition, and metabolic setpoints that resist change
Drug development has a well-documented failure rate: roughly 90% of compounds that show promise in animal models fail in human trials
For most people, the safest answer is no, not without clinical guidance and a confirmed reason
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