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There has not been a UL (upper intake level) established for B12 because it is not stored in your body and therefore, can not build up enough to cause serious adverse side effects for most people

small aliquots stored at lower temperatures extend usable life

From a clinical perspective, if blood tests reveal isolated B12 deficiency, a standalone B12 supplement or prescribed treatment would be the appropriate intervention

For a 220-pound person, that gap represents an additional 10 or more pounds lost

They can help determine the underlying cause of your symptoms and recommend the most suitable course of action

B12 injections are generally well-tolerated with mild injection site reactions, though rare hypersensitivity and hypokalaemia can occur, particularly when initiating treatment for severe deficiency