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Clinical trials have used doses of 25-30 nmol/kg by IV infusion (Schneider-Helmert et al., 1981Subcutaneous administration and oral intestinal absorption have also been studied
Animals mounted on 2% agarose pads and 20 mM sodium azide were imaged under the same parameters (63x objective, Z-stack and exposure time) on the Zeiss Axioimager Z1
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To further define the role of TEC ferroptosis in renal interstitial fibrosis, we employed adeno-associated viral vectors to overexpress GPX4 (AAV9-mGPX4) or deliver a control vector (AAV9-Vector) to renal proximal TECs (Fig