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This mechanism of action may be related to the ability of BPC 157 to up-regulate the expression of genes such as Egr1 and Vegfr2, which play important roles in the growth and differentiation of neurons
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While animal models show promising tissue repair dynamics, there is no high-quality human data confirming that oral or injectable BPC 157 can safely heal the human intestinal mucosa or cure increased intestinal permeability
The degree to which neurosteroids produce genomic and non-genomic effects depends on the extent to which they are metabolized (e.g., PREG to progesterone), and the extent to which the parent molecule and its neuroactive metabolites modulate extra- and intracellular receptors (104)
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