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GLP-1 drugs are useful tools for managing weight in people with obesity or type 2 diabetes because they regulate hunger, decrease stomach emptying, and enhance blood sugar regulation

In preclinical models, GLP-1 receptor agonists appear to modulate inflammatory signalling pathways such as nuclear factor kappa B (NF-B), a key transcription factor regulating inflammatory gene expression

At present, RNA nanomedicine has been used to achieve specific targets in the clinical treatment of eye diseases (Zhang et al., 2024)

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Internal FDA staff agreed

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