Semaglutide and tirzepatide are GLP-1 (glucagon-like peptide-1) receptor antagonists
Early tests suggest both can produce even better glucose control and weight loss than the current options
In 2021, semaglutide was FDA-approved for this purpose, under the brand name Wegovy, and it has remained the target of extensive research, demonstrating remarkable results in clinical trials
Effects of the GLP-1 Agonist Exendin-4 on Intravenous Ethanol Self-Administration in Mice
Liu, Z., Duan, X., & Yuan, M
A study from Chiou and colleagues considered that GLP-1RA could modulate the differentiation of Th1/Th17, providing mechanistic insight on T cells regulation in ameliorating experimental autoimmune encephalomyelitis by GLP-1 (Chiou et al