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The derivatives were resolved and detected using liquid chromatography/electron spray ionization/tandem mass spectrometry in multi-reaction monitoring mode

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The ratio of reduced GSH to the disulfide form (GSH/GSSG) within the endoplasmic reticulum ranges from 1:1 to 4:1, whereas the overall cellular GSH/GSSG ratio ranges from 30:1 to 100:1 (Figure 2)

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A strong combination for patients over 50 or those with concurrent fatigue and cognitive concerns

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