Alsubhi S, Osterman B, Chrestian N, Dubeau F, Buhas D, Srour M
This large muscle is easily identified on the upper, outer thigh making it a safe injection site for self-administration
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Scheduling a series of repeat appointments is also inconvenient
Clinics sometimes include GACLIV as part of IV therapy or amino acid wellness programs
Combined success rate: 8595%