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Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed

Sometimes elders do far better with drops or oral spray forms of vitamin B12 since they have problem absorbing the vitamin from the stomach

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If a supplement contains hydroxocobalamin as the only form of B12, it is most likely to have been prescribed

In these instances, elevated B12 may not be the root cause of illness but a biomarker that may signal a deeper health concern needing investigation

Adverse effects: Seek medical advice if you develop any unusual, severe, or persistent side effects or symptoms after taking vitamin B12 supplements