While your doctor can advise you, there isnt much you can do aside from changing your diet and waiting for your body to adjust to the treatment
The first gap is species
"Phytomelatonin: assisting plants to survive and thrive"
In the randomized Semaglutide Treatment Effect in People with Obesity (STEP) 1 trial (intent to treat: 1,961 adults with overweight or obesity without T2D), once-weekly subcutaneous semaglutide 2.4 mg resulted in greater weight loss compared with placebo over a 68-week period (estimated treatment difference 12.4 percentage points, 95% confidence interval (CI) 13.4, 11.5
The treatment of obesity in adolescents has additional layers of complexity, including the patients evolving maturity, family dynamics, psychiatric complexities, and social factors
[1] One trial did find that oral supplementation of glutathione did have an effect on increasing your body's level of glutathione, indicating that at least some of it does still get through your system to take effect