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The main phenotype of loss-of-function mutations in arGSTs is the decreased content of anthocyanins ( 1 ) 19,20,21,22,23,24,25,26,27,28 and proanthocyanidins 27 , which can be well explained by an incomplete biosynthesis due to the absence of an essential enzyme

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These products provide larger amounts of other sulfur derivatives such as -glutamyl-S-allylcysteine (GSAC) and S-allylcysteine (SAC), which show similar antioxidant effects as allicin

Excess bilirubin in bile due to impaired processing can result in black pigment gallstone formation, while heme accumulation can induce oxidative stress and liver damage

Overall, most clients receive their medication within 1 week from when they speak to the provider

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