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This review sets out the molecular and central nervous system biology of the GLP-1 receptor, the mechanisms proposed to underlie its neuroprotective effects, and the clinical trial record in Parkinsons and Alzheimers disease

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Anyways, I just went off too many tangents no, Thanks very much, interesting

What the Clinical Trial Evidence Shows Phase 2 trials published in NEJM (2023) reported dose-dependent mean resting heart rate increases of approximately 57 bpm at higher doses

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Whats different about semaglutide is that it changes the biological drivers of weight gain