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Participants treated with semaglutide experienced significantly diminished cravings for sweet, savory, and dairy-rich foods compared to those receiving placebo after 20 weeks of therapy and during the active phase of weight loss (Friedrichsen et al., 2021)

Patients with specific GLP1R variants may experience faster satiety on lower doses, while others may require higher maintenance levels to achieve target weight loss

95 CI 13.4 to 11.5

425 HDAC inhibitors are potential therapeutic options because the expression of HDACs is associated with poor clinical outcomes

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