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The appetite suppression is the most obvious mechanism, reducing caloric intake by 20 to 40% in most users

Pleasance ED, Cheetham RK, Stephens PJ, McBride DJ, Humphray SJ, Greenman CD et al

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Exercise improves insulin sensitivity and lowers blood glucose levels, which are essential for controlling diabetes (111, 112) and, consequently, the progression of DR (110, 113)

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