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Peak plasma concentration occurs 2448 hours post-injection, but therapeutic receptor occupancy persists throughout the seven-day interval

Under exposure to IL-1, F2-IsoPs release GM-CSF and the granulocyte colony stimulating factor (G-CSF) (37)

It has been reported that these three compounds can enhance the contents of GSH and the activities of GSH-dependent antioxidant enzymes (GPX and GST) and reduce lipid peroxidation and cardiac damage mediated by DOX or isoproterenol (ISO) in the myocardium of rats, respectively [121, 129, 130]

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