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In patients with MCAS, mobilizing toxins too quickly can trigger severe mast cell degranulation, leading to hives, flushing, gastrointestinal distress, and even anaphylaxis-like reactions

Natural IELs attain their activated phenotype during their maturation in the thymus, where they are exposed to self-antigens

However, for various reasons, animals are not provided with an adequate amount of feed

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Sustained elevation of IGF-1 is associated, in observational studies of acromegaly (a disease of GH excess), with increased risk of several cancers including colorectal and breast

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