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But results of two gold-standard trials released at the American Diabetes Associations annual meeting looked at how doses of oral semaglutide as high as 25 milligrams and 50 milligrams worked to reduce weight and improve blood sugar and other health markers
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PIONEER 3: Head-to-head vs Januvia (sitagliptin) 1,4 Study design: 78-week, randomized, double-blind, double-dummy, active controlled, parallel-group, phase 3a trial designed to assess the efficacy and assess long-term adverse event profile of once-daily semaglutide tablets vs Januvia in addition to metformin with or without sulfonylurea
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Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) approved by the FDA for the treatment of type 2 diabetes (under the brand names Ozempic and Rybelsus) and chronic weight management (as Wegovy)
