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In our initial phenotype-driven screen, 238 semi-cloned embryos were produced from Trim-library-1 and Trim-library-2, among which two embryos exhibited PGC failure, and two others showed reduced PGC numbers (Supplementary information, Fig

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BPC 157 was given per-orally, in drinking water (10 g/kg, 10 ng/kg, i.e., 0.16 g/ml, 0.16 ng/ml, and 12 ml/rat/day) till sacrifice, or alternatively, 10 g/kg and 10 ng/kg intraperitoneally

Up to sevenfold increases were observed at day three