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The copper ion coordinates with nitrogen from the imidazole side chain of histidine, the alpha-amino group of glycine, and the deprotonated amide nitrogen of the glycine-histidine peptide bond, forming a square-planar pyramid configuration

It is to support the ones that are still present but not functioning optimally

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Ferroptotic macrophages can trigger a systemic inflammatory response by releasing DAMPs and pro-inflammatory cytokines that can activate the inflammasome

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