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1 Even following the availability of new oral anticoagulant classes, it is widely used for its various indications including prophylaxis and treatment of venous thrombosis and pulmonary embolism, prophylaxis and treatment of thromboembolic complications of atrial fibrillation and heart valve replacement, and postmyocardial infarction (MI) reduction in the risk of death, recurrent MI, and thromboembolic events such as stroke or systemic embolization

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