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For example, Chinese formulations such as Xiaoyaosan and Danzhi-Xiaoyao-San have demonstrated the ability to regulate gut microbiota in animal models, leading to improved depressive behaviors

Wang Y, Parlevliet ET, Geerling JJ, van der Tuin SJ, Zhang H, Bieghs V, Jawad AH, Shiri-Sverdlov R, Bot I, de Jager SC

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Most human studies rely on small sample sizes, short intervention periods, and subjective appetite or liking scales, while lacking objective gustatory measures such as taste-threshold testing or electrogustometry (153, 173, 180, 181)