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Adding multi-day fasting to pharmacological appetite suppression creates risk of hypoglycemia, severe electrolyte imbalance, excessive muscle breakdown, nutrient deficiency, and in people with type 2 diabetes, dangerous metabolic instability

Tirzepatide's dual mechanism allows for a higher dose ceiling because the GIP component modulates the gastrointestinal effects that would otherwise limit dosing

Whether this injectable dose is sufficient to meaningfully impact NAD+ levels remains an open question

So theres higher doses that are required to produce the weight loss

Buyers should still ask their insurers

GHK-Cu may complement retinol with a better tolerability profile and different mechanistic angle