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In patients with spinal deformities, such as idiopathic scoliosis and degenerative scoliosis, the apical vertebral region experiences stress concentration, resulting in higher grades of disc degeneration compared to other regions 10,27

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10.1016/s0024-3205(01)01354-6 258 WangJ.HeF

Provider supervision, hydration, gradual dosing, proper nutrition, and safe injection technique may help reduce risks