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Procedures such as total gastrectomy, gastric bypass and Whipple procedure bypass or remove parts of the body involved in digestion and the absorption of vitamin B12

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The only requirement is that the drug gets delivered via the subcutaneous or intramuscular route, not intravenously

Pregnant women may notice a decline in their serum vitamin B12 levels

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Prednisone, like other corticosteroids should not be administered concomitantly with: - Barbiturates, carbamazepine, phenytoin, rifampin or ephedrine: these drugs enhance the metabolism of corticosteroids reducing their therapeutic action