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The glucagon receptor component is expected to provide unique metabolic effects including increased energy expenditure and enhanced hepatic lipid oxidation, which may contribute to the substantial body weight reductions observed in Phase 2 clinical trials

Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings

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However, because the medication slows gastric emptying and reduces appetite, many patients naturally find that they prefer smaller portions and may experience discomfort with large, high-fat meals

Metabolic effects of DSIP under hypoxia stress were investigated in rats subjected to short-term hypoxic conditions