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Compared to erythrocytes cultured in Ringer solution alone (T 1h =0.1% and T 48h =2.4%

Pro-inflammatory mediators are overexpressed via the mitogen-activated protein kinase (MAPK), nuclear factor kappa B (NF-KB), and activator protein 1 (AP-1) signaling pathways which not only regulate the inflammatory response, but also intensify ROS production and oxidative stress (5961)

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Significantly, the bioactivity of MO is dependent on its active ingredients, which are related to the different parts of this plant and extraction methods used

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