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Xiao W, Jiang W, Chen Z et al (2025) Advance in peptide-based drug development: delivery platforms, therapeutics and vaccines

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doi: 10.1016/j.chom.2017.12.010 158 KehrausSGorzalkaSHallmenCIqbalJMllerCEWrightADet al

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Archived from the original on 12 March 2016

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In an in vivo study, administration of MOTS-c intraperitoneally to de-ovalized osteoporotic mice once daily for 12 weeks at a dose of 5 mg/kg, lead to an increased positive trend in several bone formation parameters, such as bone mineral density, bone volume/tissue volume, bone trabecule number, and bone trabecule thickness, indicating that the MOTS-c intervention effectively reduced bone loss

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Store unopened vials at -20C (freezer) and reconstituted solutions at 2-8C (refrigerator) for optimal stability and shelf life

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