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2020 global estimate and projected number of adults through 2035 with an overweight BMI [1]

If nausea remains problematic despite conservative management strategies, healthcare providers may consider maintaining a lower dose for an extended period before further escalation, or in some cases, temporarily reducing the dose

TL;DR Don't choose something with ultra-high amounts of sodium, carbohydrates, or sugar unless you need to based on your exercise levels or a sweat test

This is due to the teratogenic effects it may cause to the developing fetus 21

GLP-1R triggers various intracellular signaling pathways, such as the cAMP/PKA and PI3K/Akt pathways, by binding to endogenous GLP-1 or exogenous agonists, resulting in the enhancement of insulin secretion, inhibition of glucagon secretion, as well as anti-inflammatory and antioxidant stress response

PMID: 15262693