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The extensive SURPASS clinical trials, encompassing eight completed studies, have evaluated tirzepatide as both monotherapy and in combination with other treatments (4)
It says together they amplify glucose-dependent insulin secretion and suppress glucagon
By leveraging this mechanism, GLP-1 medications make you feel fuller sooner and longer after eating, which can lead to reduced calorie intake and subsequent weight loss
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Leamon CP, Reddy JA
Semaglutide and tirzepatide are potent GLP-1 drugs that also trigger weight loss through appetite suppression and metabolic effects
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