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Significant reductions in HbA1c at 6 months (0.7%

Indeed, the ratio of BODIPY-PE hi mBBr hi to BODIPY-PE lo mBBr lo was significantly increased in the activated CD8 + T cells with treatment of A2ARi plus Lip-1 compared with A2ARi or Lip-1 treatment alone (Figure 5J)

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Given the complex and heterogeneous trajectory of FFM during weight regain and considering that FFM is a broader, less metabolically strategic compartment than specific lean mass, as previously discussed, evaluating the qualitative deterioration of muscle tissue emerges as a more critical objective